It is now 12 years since publication of the original Durban classification criteria for juvenile idiopathic arthritis (J. Rheumatol. 1998;25:1991-4) and 9 years since the revision in Edmonton (J. Rheumatol. 2004;31:390-2 ). Yet the majority of adult rheumatologists, the public, and even many pediatric rheumatologists continue to believe that the new criteria simply substituted an I for an R (JIA instead of JRA) to emphasize that most childhood arthritis is not related to the rheumatoid...

BOSTON (EGMN) – Morphine is a poor candidate for transdermal drug delivery, Judith Paice, Ph.D., said at the annual meeting of the American Academy of Hospice and Palliative Medicine.Dr. Paice said she and her colleagues conducted a small study to assess the bioavailability of a topical formulation of morphine relative to the 100% bioavailable subcutaneous dose, but in blood samples collected from the participants beginning 5 minutes to 10 hours after dose administration “we seldom detected...